在接受检查过程中,由于受试者不愿配合、或突发的系统故障而导致系统无法继续进行检查、受试者突发临床症状需要急救导致检查中断,这些不良事件都可能导致受试者中途退出,从而加长临床试验时间。在接受检查过程中,由于受试者的原因造成图像质量不能达到诊断要求,如过多的呼吸运动伪影、移动伪影、金属伪影而造成图像质量的下降,从而影响图像质量评分,最终影响到试验关于肿块可见性的结论。
During the examination, adverse events may occur, including unwillingness of the subject to cooperate, a sudden system failure making it impossible to continue the examination, or a sudden symptom of the subject requiring first aid and interruption of the examination. These events may result in drop-out of the patient and consequently longer clinical trial time. During the examination, the image quality may fail to reach diagnosis requirements due to reasons of the subject such as image quality degradation caused by excessive respiratory exercise artifact, movement artifact, or metal artifact. Such factors will impact image quality score and ultimately conclusions about mass visibility.